BDBM50532173 CHEMBL4536443

SMILES: CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N

InChI Key: InChIKey=HJWSLDFYCQJXLZ-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50532173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human C-terminal FLAG-tagged KDM6B (1043 to end residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K27(Me3)-G...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Lysine-specific demethylase 7A/7B (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal FLAG-tagged KDM7B (2 to 525 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K9(Me2)-GGK(Bio...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 350 residues) expressed in Escherichia coli using H3(21-44)-K36(Me3)-GK(Biotin)/2-OG as substra...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair
Homo sapiens lysine demethylase 2A (KDM2A) (Homo sapiens (Human))	BDBM50532173 (CHEMBL4536443) Show SMILES CCCCCCN(C)Cc1ccc(cc1)-c1[nH]c2c(cnn2c(=O)c1C(C)C)C#N Show InChI InChI=1S/C24H31N5O/c1-5-6-7-8-13-28(4)16-18-9-11-19(12-10-18)22-21(17(2)3)24(30)29-23(27-22)20(14-25)15-26-29/h9-12,15,17,27H,5-8,13,16H2,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal FLAG/Avi-tagged KDM2A (2 to 700 residues) expressed in baculovirus infected Sf9 insect cells using H3(21-44)-K36(Me2)-...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair