BDBM50532174 CHEMBL4446067

SMILES: CCCCCCN(C)CCNC(=O)c1ccnc(c1)-c1cc(ccn1)C(O)=O

InChI Key: InChIKey=GIUZQCRIIBPLIJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50532174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM50532174 (CHEMBL4446067) Show SMILES CCCCCCN(C)CCNC(=O)c1ccnc(c1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C21H28N4O3/c1-3-4-5-6-12-25(2)13-11-24-20(26)16-7-9-22-18(14-16)19-15-17(21(27)28)8-10-23-19/h7-10,14-15H,3-6,11-13H2,1-2H3,(H,24,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...				Bioorg Med Chem 27: 1119-1129 (2019) Article DOI: 10.1016/j.bmc.2019.02.006
					More data for this Ligand-Target Pair