Found 4 hits for monomerid = 50532854 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50532854
(CHEMBL4588569)Show SMILES CC1(C)CC(=O)c2c(C1)nc1n(Cc3ccccc3)cc(C#N)c1c2-c1c(F)cccc1F |(64.49,-40.46,;65.82,-39.68,;64.89,-38.49,;66.31,-41.17,;67.81,-41.5,;68.03,-43.03,;68.84,-40.35,;68.36,-38.89,;66.86,-38.57,;69.39,-37.75,;70.89,-38.06,;72.13,-37.16,;72.13,-35.62,;70.8,-34.84,;70.8,-33.3,;69.46,-32.54,;68.13,-33.31,;68.13,-34.86,;69.47,-35.62,;73.38,-38.06,;72.9,-39.53,;73.81,-40.78,;74.71,-42.03,;71.36,-39.53,;70.34,-40.66,;71.1,-43.01,;72.61,-43.32,;73.64,-42.17,;73.09,-44.79,;72.06,-45.94,;70.55,-45.62,;70.08,-44.12,;68.57,-43.77,)| Show InChI InChI=1S/C27H21F2N3O/c1-27(2)11-20-24(21(33)12-27)25(23-18(28)9-6-10-19(23)29)22-17(13-30)15-32(26(22)31-20)14-16-7-4-3-5-8-16/h3-10,15H,11-12,14H2,1-2H3 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m... |
Bioorg Med Chem Lett 26: 4101-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.065 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50532854
(CHEMBL4588569)Show SMILES CC1(C)CC(=O)c2c(C1)nc1n(Cc3ccccc3)cc(C#N)c1c2-c1c(F)cccc1F |(64.49,-40.46,;65.82,-39.68,;64.89,-38.49,;66.31,-41.17,;67.81,-41.5,;68.03,-43.03,;68.84,-40.35,;68.36,-38.89,;66.86,-38.57,;69.39,-37.75,;70.89,-38.06,;72.13,-37.16,;72.13,-35.62,;70.8,-34.84,;70.8,-33.3,;69.46,-32.54,;68.13,-33.31,;68.13,-34.86,;69.47,-35.62,;73.38,-38.06,;72.9,-39.53,;73.81,-40.78,;74.71,-42.03,;71.36,-39.53,;70.34,-40.66,;71.1,-43.01,;72.61,-43.32,;73.64,-42.17,;73.09,-44.79,;72.06,-45.94,;70.55,-45.62,;70.08,-44.12,;68.57,-43.77,)| Show InChI InChI=1S/C27H21F2N3O/c1-27(2)11-20-24(21(33)12-27)25(23-18(28)9-6-10-19(23)29)22-17(13-30)15-32(26(22)31-20)14-16-7-4-3-5-8-16/h3-10,15H,11-12,14H2,1-2H3 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub... |
Bioorg Med Chem Lett 26: 4101-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.065 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50532854
(CHEMBL4588569)Show SMILES CC1(C)CC(=O)c2c(C1)nc1n(Cc3ccccc3)cc(C#N)c1c2-c1c(F)cccc1F |(64.49,-40.46,;65.82,-39.68,;64.89,-38.49,;66.31,-41.17,;67.81,-41.5,;68.03,-43.03,;68.84,-40.35,;68.36,-38.89,;66.86,-38.57,;69.39,-37.75,;70.89,-38.06,;72.13,-37.16,;72.13,-35.62,;70.8,-34.84,;70.8,-33.3,;69.46,-32.54,;68.13,-33.31,;68.13,-34.86,;69.47,-35.62,;73.38,-38.06,;72.9,-39.53,;73.81,-40.78,;74.71,-42.03,;71.36,-39.53,;70.34,-40.66,;71.1,-43.01,;72.61,-43.32,;73.64,-42.17,;73.09,-44.79,;72.06,-45.94,;70.55,-45.62,;70.08,-44.12,;68.57,-43.77,)| Show InChI InChI=1S/C27H21F2N3O/c1-27(2)11-20-24(21(33)12-27)25(23-18(28)9-6-10-19(23)29)22-17(13-30)15-32(26(22)31-20)14-16-7-4-3-5-8-16/h3-10,15H,11-12,14H2,1-2H3 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m... |
Bioorg Med Chem Lett 26: 4101-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.065 |
More data for this
Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50532854
(CHEMBL4588569)Show SMILES CC1(C)CC(=O)c2c(C1)nc1n(Cc3ccccc3)cc(C#N)c1c2-c1c(F)cccc1F |(64.49,-40.46,;65.82,-39.68,;64.89,-38.49,;66.31,-41.17,;67.81,-41.5,;68.03,-43.03,;68.84,-40.35,;68.36,-38.89,;66.86,-38.57,;69.39,-37.75,;70.89,-38.06,;72.13,-37.16,;72.13,-35.62,;70.8,-34.84,;70.8,-33.3,;69.46,-32.54,;68.13,-33.31,;68.13,-34.86,;69.47,-35.62,;73.38,-38.06,;72.9,-39.53,;73.81,-40.78,;74.71,-42.03,;71.36,-39.53,;70.34,-40.66,;71.1,-43.01,;72.61,-43.32,;73.64,-42.17,;73.09,-44.79,;72.06,-45.94,;70.55,-45.62,;70.08,-44.12,;68.57,-43.77,)| Show InChI InChI=1S/C27H21F2N3O/c1-27(2)11-20-24(21(33)12-27)25(23-18(28)9-6-10-19(23)29)22-17(13-30)15-32(26(22)31-20)14-16-7-4-3-5-8-16/h3-10,15H,11-12,14H2,1-2H3 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub... |
Bioorg Med Chem Lett 26: 4101-5 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.065 |
More data for this
Ligand-Target Pair | |
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