BDBM50533084 CHEMBL4447634

SMILES: O=C(N1CCn2nc(cc2C1)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=QBIPJEOESUZIMF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50533084 (CHEMBL4447634) Show SMILES O=C(N1CCn2nc(cc2C1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H17N3O/c23-19(16-9-5-2-6-10-16)21-11-12-22-17(14-21)13-18(20-22)15-7-3-1-4-8-15/h1-10,13H,11-12,14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd Curated by ChEMBL					Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...				Bioorg Med Chem Lett 26: 3866-9 (2016) Article DOI: 10.1016/j.bmcl.2016.07.019
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50533084 (CHEMBL4447634) Show SMILES O=C(N1CCn2nc(cc2C1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H17N3O/c23-19(16-9-5-2-6-10-16)21-11-12-22-17(14-21)13-18(20-22)15-7-3-1-4-8-15/h1-10,13H,11-12,14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd Curated by ChEMBL					Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as L-glutamate-induced intracellular calcium mobilizati...				Bioorg Med Chem Lett 26: 3866-9 (2016) Article DOI: 10.1016/j.bmcl.2016.07.019
					More data for this Ligand-Target Pair