Found 4 hits for monomerid = 50533149 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
1,3-beta-glucan synthase component GLS2
(Saccharomyces cerevisiae) | BDBM50533149
(CHEMBL4438583)Show SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1 Show InChI InChI=1S/C24H26N6O4/c1-16-19(6-7-20-21(16)14-34-24(20)33)22(31)13-28-8-10-29(11-9-28)23(32)12-17-2-4-18(5-3-17)30-15-25-26-27-30/h2-7,15,22,31H,8-14H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]MK-499 from human ERG |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this Ligand-Target Pair | |
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50533149
(CHEMBL4438583)Show SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1 Show InChI InChI=1S/C24H26N6O4/c1-16-19(6-7-20-21(16)14-34-24(20)33)22(31)13-28-8-10-29(11-9-28)23(32)12-17-2-4-18(5-3-17)30-15-25-26-27-30/h2-7,15,22,31H,8-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assay |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this Ligand-Target Pair | |
1,3-beta-glucan synthase component GLS2
(Saccharomyces cerevisiae) | BDBM50533149
(CHEMBL4438583)Show SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1 Show InChI InChI=1S/C24H26N6O4/c1-16-19(6-7-20-21(16)14-34-24(20)33)22(31)13-28-8-10-29(11-9-28)23(32)12-17-2-4-18(5-3-17)30-15-25-26-27-30/h2-7,15,22,31H,8-14H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [35S]MK-499 from human ERG |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this Ligand-Target Pair | |
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50533149
(CHEMBL4438583)Show SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1 Show InChI InChI=1S/C24H26N6O4/c1-16-19(6-7-20-21(16)14-34-24(20)33)22(31)13-28-8-10-29(11-9-28)23(32)12-17-2-4-18(5-3-17)30-15-25-26-27-30/h2-7,15,22,31H,8-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assay |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this Ligand-Target Pair | |