Found 4 hits for monomerid = 50533151 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50533151
(CHEMBL4534171)Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc3C(=O)OCc3c2C)CC1 Show InChI InChI=1S/C26H30N2O4/c1-17-19(3-5-21-23(17)15-31-25(21)29)7-9-27-11-13-28(14-12-27)10-8-20-4-6-22-24(18(20)2)16-32-26(22)30/h3-6H,7-16H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assay |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this
Ligand-Target Pair | |
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50533151
(CHEMBL4534171)Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc3C(=O)OCc3c2C)CC1 Show InChI InChI=1S/C26H30N2O4/c1-17-19(3-5-21-23(17)15-31-25(21)29)7-9-27-11-13-28(14-12-27)10-8-20-4-6-22-24(18(20)2)16-32-26(22)30/h3-6H,7-16H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of ROMK (unknown origin) after 30 mins by 86Rb+ efflux assay |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this
Ligand-Target Pair | |
1,3-beta-glucan synthase component GLS2
(Saccharomyces cerevisiae) | BDBM50533151
(CHEMBL4534171)Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc3C(=O)OCc3c2C)CC1 Show InChI InChI=1S/C26H30N2O4/c1-17-19(3-5-21-23(17)15-31-25(21)29)7-9-27-11-13-28(14-12-27)10-8-20-4-6-22-24(18(20)2)16-32-26(22)30/h3-6H,7-16H2,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK-499 from human ERG |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this
Ligand-Target Pair | |
1,3-beta-glucan synthase component GLS2
(Saccharomyces cerevisiae) | BDBM50533151
(CHEMBL4534171)Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc3C(=O)OCc3c2C)CC1 Show InChI InChI=1S/C26H30N2O4/c1-17-19(3-5-21-23(17)15-31-25(21)29)7-9-27-11-13-28(14-12-27)10-8-20-4-6-22-24(18(20)2)16-32-26(22)30/h3-6H,7-16H2,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [35S]MK-499 from human ERG |
ACS Med Chem Lett 7: 697-701 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00122 |
More data for this
Ligand-Target Pair | |
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