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SMILES: Cc1nn(CC2CCCC2)nc1-c1ncnc2[nH]ccc12

InChI Key: InChIKey=AMQAEOAHHYUBRJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50533712   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM50533712
PNG
(CHEMBL4518995)
Show SMILES Cc1nn(CC2CCCC2)nc1-c1ncnc2[nH]ccc12
Show InChI InChI=1S/C15H18N6/c1-10-13(14-12-6-7-16-15(12)18-9-17-14)20-21(19-10)8-11-4-2-3-5-11/h6-7,9,11H,2-5,8H2,1H3,(H,16,17,18)
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n/an/a 72n/an/an/an/an/an/a



Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal 6His-tagged JAK2 (808 to end amino acids) expressed in Sf21 cells measured after 1 hr in presence of ATP b...

Bioorg Med Chem 24: 5036-5046 (2016)


Article DOI: 10.1016/j.bmc.2016.08.008
More data for this
Ligand-Target Pair