BDBM50534279 CHEMBL4468927

SMILES: NC(=O)c1ccc(Cc2ccccc2)cc1-c1cccc(CC(O)=O)c1

InChI Key: InChIKey=BURBMNTYEMRUAU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50534279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50534279 (CHEMBL4468927) Show SMILES NC(=O)c1ccc(Cc2ccccc2)cc1-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C22H19NO3/c23-22(26)19-10-9-17(11-15-5-2-1-3-6-15)13-20(19)18-8-4-7-16(12-18)14-21(24)25/h1-10,12-13H,11,14H2,(H2,23,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca Curated by ChEMBL					Assay Description Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...				ACS Med Chem Lett 7: 884-889 (2016) Article DOI: 10.1021/acsmedchemlett.6b00188
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50534279 (CHEMBL4468927) Show SMILES NC(=O)c1ccc(Cc2ccccc2)cc1-c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C22H19NO3/c23-22(26)19-10-9-17(11-15-5-2-1-3-6-15)13-20(19)18-8-4-7-16(12-18)14-21(24)25/h1-10,12-13H,11,14H2,(H2,23,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Astrazeneca Curated by ChEMBL					Assay Description Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...				ACS Med Chem Lett 7: 884-889 (2016) Article DOI: 10.1021/acsmedchemlett.6b00188
					More data for this Ligand-Target Pair