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BDBM50535228 CHEMBL4467138

SMILES: OC(=O)C(O)=O.CC1CCN(CCCCCCOc2ccc(cc2)-c2ccccc2)CC1

InChI Key: InChIKey=GCBQHVKKHGIPPA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535228   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50535228
PNG
(CHEMBL4467138)
Show SMILES OC(=O)C(O)=O.CC1CCN(CCCCCCOc2ccc(cc2)-c2ccccc2)CC1
Show InChI InChI=1S/C24H33NO/c1-21-15-18-25(19-16-21)17-7-2-3-8-20-26-24-13-11-23(12-14-24)22-9-5-4-6-10-22/h4-6,9-14,21H,2-3,7-8,15-20H2,1H3
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Article
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 266n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human recombinant full length H3R expressed in HEK293 cell membranes incubated for 90 mins by liqui...

Bioorg Med Chem 25: 5341-5354 (2017)


Article DOI: 10.1016/j.bmc.2017.07.058
More data for this
Ligand-Target Pair