BDBM50535237 CHEMBL4575154

SMILES: CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=ZBEKHFIPWNOGJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase (Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)	BDBM50535237 (CHEMBL4575154) Show SMILES CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C16H14ClFN2O4S/c1-10(21)20-6-7-24-16-9-12(3-5-15(16)20)25(22,23)19-11-2-4-14(18)13(17)8-11/h2-5,8-9,19H,6-7H2,1H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
France; Universit£ Paris Diderot Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa IMPDH using IMP as substrate in the presence of NAD+ incubated for 70 secs				Eur J Med Chem 167: 124-132 (2019) Article DOI: 10.1016/j.ejmech.2019.01.064
					More data for this Ligand-Target Pair