BDBM50535328 CHEMBL4567879

SMILES: O=C(NCc1ccccc1)Nc1cccc(NC(=O)c2ccccn2)c1

InChI Key: InChIKey=VHWMVBCOAYPSPG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50535328 (CHEMBL4567879) Show SMILES O=C(NCc1ccccc1)Nc1cccc(NC(=O)c2ccccn2)c1 Show InChI InChI=1S/C20H18N4O2/c25-19(18-11-4-5-12-21-18)23-16-9-6-10-17(13-16)24-20(26)22-14-15-7-2-1-3-8-15/h1-13H,14H2,(H,23,25)(H2,22,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA method				Eur J Med Chem 168: 315-329 (2019) Article DOI: 10.1016/j.ejmech.2019.02.050
					More data for this Ligand-Target Pair