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SMILES: CC1(C)N(C(=O)N(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key: InChIKey=CHCSARAOOUZFEO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535839   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Rattus norvegicus (Rat))		BDBM50535839
PNG
(CHEMBL4577418)
Show SMILES CC1(C)N(C(=O)N(C1=O)c1ccc(cc1)C(F)(F)F)c1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C19H13F6N3O4/c1-17(2)15(29)26(11-5-3-10(4-6-11)18(20,21)22)16(30)27(17)12-7-8-14(28(31)32)13(9-12)19(23,24)25/h3-9H,1-2H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 80n/an/an/an/an/an/a



School of Pharmacy and Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ...

Eur J Med Chem 118: 230-43 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.052
BindingDB Entry DOI: 10.7270/Q2K35Z5N
More data for this
Ligand-Target Pair