BDBM50536166 CHEMBL4565210

SMILES: Cl.Cc1cnc2n(c(nc2c1)-c1cccnc1N)-c1ccc(CN)cc1

InChI Key: InChIKey=PNKRHUGUFAPIKL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50536166 (CHEMBL4565210) Show SMILES Cl.Cc1cnc2n(c(nc2c1)-c1cccnc1N)-c1ccc(CN)cc1 Show InChI InChI=1S/C19H18N6/c1-12-9-16-19(23-11-12)25(14-6-4-13(10-20)5-7-14)18(24-16)15-3-2-8-22-17(15)21/h2-9,11H,10,20H2,1H3,(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ArQule Inc. Curated by ChEMBL					Assay Description Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...				J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM50536166 (CHEMBL4565210) Show SMILES Cl.Cc1cnc2n(c(nc2c1)-c1cccnc1N)-c1ccc(CN)cc1 Show InChI InChI=1S/C19H18N6/c1-12-9-16-19(23-11-12)25(14-6-4-13(10-20)5-7-14)18(24-16)15-3-2-8-22-17(15)21/h2-9,11H,10,20H2,1H3,(H2,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ArQule Inc. Curated by ChEMBL					Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...				J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50536166 (CHEMBL4565210) Show SMILES Cl.Cc1cnc2n(c(nc2c1)-c1cccnc1N)-c1ccc(CN)cc1 Show InChI InChI=1S/C19H18N6/c1-12-9-16-19(23-11-12)25(14-6-4-13(10-20)5-7-14)18(24-16)15-3-2-8-22-17(15)21/h2-9,11H,10,20H2,1H3,(H2,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
ArQule Inc. Curated by ChEMBL					Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...				J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619
					More data for this Ligand-Target Pair