BDBM50536175 CHEMBL4558319

SMILES: Cl.NCc1ccc(cc1)-n1c(nc2cc(Br)cnc12)-c1cccnc1N

InChI Key: InChIKey=OMQZNKIQMWDSNI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50536175 (CHEMBL4558319) Show SMILES Cl.NCc1ccc(cc1)-n1c(nc2cc(Br)cnc12)-c1cccnc1N Show InChI InChI=1S/C18H15BrN6/c19-12-8-15-18(23-10-12)25(13-5-3-11(9-20)4-6-13)17(24-15)14-2-1-7-22-16(14)21/h1-8,10H,9,20H2,(H2,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
ArQule Inc. Curated by ChEMBL					Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-...				J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619
					More data for this Ligand-Target Pair