BDBM50536449 CHEMBL4563141
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1
InChI Key: InChIKey=CVCLWRHUFDCDLK-KGSCVCOFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human)) | BDBM50536449 (CHEMBL4563141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co... | J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human)) | BDBM50536449 (CHEMBL4563141) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden Institute of Chemistry Curated by ChEMBL | Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b... | J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 | |||||||||||
More data for this Ligand-Target Pair |