BDBM50536926 CHEMBL4559055

SMILES: O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCCc1ccccc1)NC1CC1

InChI Key: InChIKey=INGKYJLJBNXEDF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM50536926 (CHEMBL4559055) Show SMILES O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCCc1ccccc1)NC1CC1 Show InChI InChI=1S/C24H25N5O2S2/c30-22(25-18-12-13-18)16-32-23-27-26-21(28(23)14-6-9-17-7-2-1-3-8-17)15-29-19-10-4-5-11-20(19)33-24(29)31/h1-5,7-8,10-11,18H,6,9,12-16H2,(H,25,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISA				Eur J Med Chem 165: 80-92 (2019) Article DOI: 10.1016/j.ejmech.2019.01.008
					More data for this Ligand-Target Pair