BDBM50537006 CHEMBL4521321

SMILES: CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)N(C)C

InChI Key: InChIKey=MAFIZZVLWBRVSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50537006 (CHEMBL4521321) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1CCOC)C(=O)NS(=O)(=O)N(C)C Show InChI InChI=1S/C27H29N5O4S/c1-5-31-23-9-7-6-8-20(23)21-16-18(10-12-24(21)31)26-28-22-17-19(27(33)29-37(34,35)30(2)3)11-13-25(22)32(26)14-15-36-4/h6-13,16-17H,5,14-15H2,1-4H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human EP4R assessed as inhibition of agonist-induced cAMP production by fluorescent cAMP tracer cAMP-d2 based FRET assay				J Med Chem 62: 2541-2563 (2019) Article DOI: 10.1021/acs.jmedchem.8b01862
					More data for this Ligand-Target Pair