BDBM50537184 CHEMBL4514254

SMILES: COc1cnc(OC)c(c1)C(O)(CCN(C)C)C(c1cccc(OC)c1F)c1cc2cc(Br)ccc2nc1OC

InChI Key: InChIKey=ZCVOKXSJKIJDQO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50537184 (CHEMBL4514254) Show SMILES COc1cnc(OC)c(c1)C(O)(CCN(C)C)C(c1cccc(OC)c1F)c1cc2cc(Br)ccc2nc1OC Show InChI InChI=1S/C30H33BrFN3O5/c1-35(2)13-12-30(36,23-16-20(37-3)17-33-29(23)40-6)26(21-8-7-9-25(38-4)27(21)32)22-15-18-14-19(31)10-11-24(18)34-28(22)39-5/h7-11,14-17,26,36H,12-13H2,1-6H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human ERG by manual patch clamp electrophysiology assay				Bioorg Med Chem 27: 1283-1291 (2019) Article DOI: 10.1016/j.bmc.2019.02.025
					More data for this Ligand-Target Pair