BDBM50537547 CHEMBL4645337

SMILES: CC(C)n1cc(C2=C(C(=O)NC2=O)c2cccc(NC(=O)CF)c2)c2cccnc12

InChI Key: InChIKey=DYECYVRAAJOEPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50537547 (CHEMBL4645337) Show SMILES CC(C)n1cc(C2=C(C(=O)NC2=O)c2cccc(NC(=O)CF)c2)c2cccnc12 |t:6| Show InChI InChI=1S/C22H19FN4O3/c1-12(2)27-11-16(15-7-4-8-24-20(15)27)19-18(21(29)26-22(19)30)13-5-3-6-14(9-13)25-17(28)10-23/h3-9,11-12H,10H2,1-2H3,(H,25,28)(H,26,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of Protein kinase C alpha				Eur J Med Chem 164: 448-470 (2019) Article DOI: 10.1007/s00044-005-0126-y BindingDB Entry DOI: 10.7270/Q2WH2SVB
					More data for this Ligand-Target Pair