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BDBM50537562 CHEMBL223720

SMILES: CN(C)CC1CNc2nc3ccc4OCC(CN(C)C)Cc4c3n2C1

InChI Key: InChIKey=FIPRRHYNEZXZGC-UHFFFAOYSA-N

Data: 1 Kd

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537562   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)		BDBM50537562
PNG
(CHEMBL223720)
Show SMILES CN(C)CC1CNc2nc3ccc4OCC(CN(C)C)Cc4c3n2C1
Show InChI InChI=1S/C19H29N5O/c1-22(2)9-13-7-15-17(25-12-13)6-5-16-18(15)24-11-14(10-23(3)4)8-20-19(24)21-16/h5-6,13-14H,7-12H2,1-4H3,(H,20,21)
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 720n/an/an/an/an/a



Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells

Eur J Med Chem 164: 576-601 (2019)


Article DOI: 10.1007/s00044-005-0131-1
BindingDB Entry DOI: 10.7270/Q2RR224D
More data for this
Ligand-Target Pair