BDBM50537720 CHEMBL4641286

SMILES: [H][C@]12CN(c3nc(ncc3C#N)-c3ccccc3)[C@]([H])(CN1c1cccc(F)c1)C2

InChI Key: InChIKey=AYLOKWSHQAMLFR-PMACEKPBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50537720 (CHEMBL4641286) Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3ccccc3)[C@]([H])(CN1c1cccc(F)c1)C2 |r| Show InChI InChI=1S/C22H18FN5/c23-17-7-4-8-18(9-17)27-13-20-10-19(27)14-28(20)22-16(11-24)12-25-21(26-22)15-5-2-1-3-6-15/h1-9,12,19-20H,10,13-14H2/t19-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition Protein kinase C gamma				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair