BDBM50537725 CHEMBL4635168
SMILES: [H][C@]12CN(c3nc(ncc3C#N)-c3cnn(C)c3)[C@]([H])(CN1C(=O)C1CC1)C2
InChI Key: InChIKey=BAPNSRDKEKRQFX-GJZGRUSLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50537725 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphoinositide 3-Kinase (PI3K), delta
(Homo sapiens (Human)) | BDBM50537725
(CHEMBL4635168)Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3cnn(C)c3)[C@]([H])(CN1C(=O)C1CC1)C2 |r| Show InChI InChI=1S/C18H19N7O/c1-23-8-13(7-21-23)16-20-6-12(5-19)17(22-16)24-9-15-4-14(24)10-25(15)18(26)11-2-3-11/h6-8,11,14-15H,2-4,9-10H2,1H3/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell... |
Bioorg Med Chem Lett 30: (2020)
|
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50537725
(CHEMBL4635168)Show SMILES [H][C@]12CN(c3nc(ncc3C#N)-c3cnn(C)c3)[C@]([H])(CN1C(=O)C1CC1)C2 |r| Show InChI InChI=1S/C18H19N7O/c1-23-8-13(7-21-23)16-20-6-12(5-19)17(22-16)24-9-15-4-14(24)10-25(15)18(26)11-2-3-11/h6-8,11,14-15H,2-4,9-10H2,1H3/t14-,15-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 258 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibition of the fibroblast growth factor receptor (FGFR1) |
Bioorg Med Chem Lett 30: (2020)
|
More data for this
Ligand-Target Pair | |
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