BDBM50537729 CHEMBL4644811

SMILES: Cn1cc(cn1)-c1ncc(C#N)c(n1)N1CCN(CC1)c1cccc(F)c1

InChI Key: InChIKey=LVYWVOBKHHMZRO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50537729 (CHEMBL4644811) Show SMILES Cn1cc(cn1)-c1ncc(C#N)c(n1)N1CCN(CC1)c1cccc(F)c1 Show InChI InChI=1S/C19H18FN7/c1-25-13-15(12-23-25)18-22-11-14(10-21)19(24-18)27-7-5-26(6-8-27)17-4-2-3-16(20)9-17/h2-4,9,11-13H,5-8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair