BDBM50537736 CHEMBL4646437

SMILES: C[C@@H]1CN(CCN1C(=O)C1(C)CC1)c1nc(ncc1C#N)-c1cnn(C)c1

InChI Key: InChIKey=MSDVUBZPLFKQFG-CYBMUJFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50537736 (CHEMBL4646437) Show SMILES C[C@@H]1CN(CCN1C(=O)C1(C)CC1)c1nc(ncc1C#N)-c1cnn(C)c1 |r| Show InChI InChI=1S/C19H23N7O/c1-13-11-25(6-7-26(13)18(27)19(2)4-5-19)17-14(8-20)9-21-16(23-17)15-10-22-24(3)12-15/h9-10,12-13H,4-7,11H2,1-3H3/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50537736 (CHEMBL4646437) Show SMILES C[C@@H]1CN(CCN1C(=O)C1(C)CC1)c1nc(ncc1C#N)-c1cnn(C)c1 |r| Show InChI InChI=1S/C19H23N7O/c1-13-11-25(6-7-26(13)18(27)19(2)4-5-19)17-14(8-20)9-21-16(23-17)15-10-22-24(3)12-15/h9-10,12-13H,4-7,11H2,1-3H3/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	5.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of the fibroblast growth factor receptor (FGFR1)				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair