BDBM50538153 CHEMBL4648067

SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)C(F)(F)F)C(=O)[C@@]1(C)CO1

InChI Key: InChIKey=HVPKQMQDHYGYDU-XNCCSTQDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-9 (Homo sapiens (Human))	BDBM50538153 (CHEMBL4648067) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)C(F)(F)F)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C27H35F3N4O6/c1-16(2)12-18(22(36)26(3)15-40-26)32-23(37)19(13-17-8-5-4-6-9-17)33-24(38)20-10-7-11-34(20)21(35)14-31-25(39)27(28,29)30/h4-6,8-9,16,18-20H,7,10-15H2,1-3H3,(H,31,39)(H,32,37)(H,33,38)/t18-,19-,20-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysis				J Med Chem 63: 3763-3783 (2020)
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