null
SMILES: Fc1ccc(cc1)-c1cccn2cc(nc12)-c1ccccc1
InChI Key: InChIKey=KYEUASGECWTDSZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldehyde dehydrogenase family 1 member A3 (Homo sapiens (Human)) | BDBM50538687 (CHEMBL4637120) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pisa Curated by ChEMBL | Assay Description Inhibition of human recombinant ALDH1A3 pre-incubated for 5 mins before acetaldehyde addition by continuous spectrometric assay relative to control | ACS Med Chem Lett 11: 963-970 (2020) | |||||||||||
More data for this Ligand-Target Pair |