BDBM50539118 CHEMBL4643228

SMILES: CN1c2ccc(NC(=S)Nc3ccc(cc3)C(F)(F)F)cc2C(C)(C)C(O)C1(C)C

InChI Key: InChIKey=VBTDJOSBTQDKPN-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stress-70 protein, mitochondrial (Homo sapiens)	BDBM50539118 (CHEMBL4643228) Show SMILES CN1c2ccc(NC(=S)Nc3ccc(cc3)C(F)(F)F)cc2C(C)(C)C(O)C1(C)C Show InChI InChI=1S/C22H26F3N3OS/c1-20(2)16-12-15(10-11-17(16)28(5)21(3,4)18(20)29)27-19(30)26-14-8-6-13(7-9-14)22(23,24)25/h6-12,18,29H,1-5H3,(H2,26,27,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
Oklahoma State University Curated by ChEMBL					Assay Description Binding affinity to mortalin substrate binding domain (unknown origin)				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair