BDBM50539250 CHEMBL4635420

SMILES: OC(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1

InChI Key: InChIKey=OOHSFJBWQHJQBM-DEOSSOPVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-2 (Mus musculus)	BDBM50539250 (CHEMBL4635420) Show SMILES OC(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C27H26N2O5/c30-25-15-14-24(29(25)17-20-4-2-1-3-5-20)26(31)28-16-19-8-12-23(13-9-19)34-18-21-6-10-22(11-7-21)27(32)33/h1-13,24H,14-18H2,(H,28,31)(H,32,33)/t24-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National and Kapodistrian University of Athens Curated by ChEMBL					Assay Description Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair