BDBM50539262 CHEMBL4641981

SMILES: CC1(C)OB(OC1(C)C)c1ccc(COc2ccc(CNC(=O)[C@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1

InChI Key: InChIKey=FOSFJBPUGKWVQW-MUUNZHRXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-2 (Mus musculus)	BDBM50539262 (CHEMBL4641981) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(COc2ccc(CNC(=O)[C@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C32H37BN2O5/c1-31(2)32(3,4)40-33(39-31)26-14-10-25(11-15-26)22-38-27-16-12-23(13-17-27)20-34-30(37)28-18-19-29(36)35(28)21-24-8-6-5-7-9-24/h5-17,28H,18-22H2,1-4H3,(H,34,37)/t28-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
National and Kapodistrian University of Athens Curated by ChEMBL					Assay Description Inhibition of recombinant mouse N-terminal polyHis-tagged ATX-beta (Ser49 to Ile862 residues) expressed in HEK293 cells assessed as reduction in clea...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair