BDBM50539558 CHEMBL4642997

SMILES: CCn1nnc2c(C)c(ccc12)[C@@H](CC(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=QWEGWMZKDCZIDH-QFIPXVFZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50539558 (CHEMBL4642997) Show SMILES CCn1nnc2c(C)c(ccc12)[C@@H](CC(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C28H26Cl2N4O3/c1-3-34-25-9-7-21(16(2)27(25)31-32-34)22(14-26(35)36)18-5-4-17-10-11-33(15-20(17)12-18)28(37)19-6-8-23(29)24(30)13-19/h4-9,12-13,22H,3,10-11,14-15H2,1-2H3,(H,35,36)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a
Biogen Curated by ChEMBL					Assay Description Induction of Nrf2 nuclear translocation in human U2OS cells				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair