BDBM50539630 CHEMBL4637921

SMILES: COc1cc(ccc1Nc1ncc2NC(=O)c3ccccc3N(C)c2n1)N1CCOCC1

InChI Key: InChIKey=XGGRRICOJPCUKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50539630 (CHEMBL4637921) Show SMILES COc1cc(ccc1Nc1ncc2NC(=O)c3ccccc3N(C)c2n1)N1CCOCC1 Show InChI InChI=1S/C23H24N6O3/c1-28-19-6-4-3-5-16(19)22(30)25-18-14-24-23(27-21(18)28)26-17-8-7-15(13-20(17)31-2)29-9-11-32-12-10-29/h3-8,13-14H,9-12H2,1-2H3,(H,25,30)(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 catalytic domain (110 to 476 residues) expressed in baculovirus expression syst...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair