BDBM50539786 CHEMBL4640133

SMILES: CCS(=O)(=O)Nc1cc(cc2n(Cc3ccc(F)cc3)ccc12)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=FUKCVOWFVIKRIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539786 (CHEMBL4640133) Show SMILES CCS(=O)(=O)Nc1cc(cc2n(Cc3ccc(F)cc3)ccc12)-c1cn(C)c2c1cc[nH]c2=O Show InChI InChI=1S/C25H23FN4O3S/c1-3-34(32,33)28-22-12-17(21-15-29(2)24-19(21)8-10-27-25(24)31)13-23-20(22)9-11-30(23)14-16-4-6-18(26)7-5-16/h4-13,15,28H,3,14H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair