BDBM50539787 CHEMBL4634252

SMILES: Cn1cc(-c2cc(NS(C)(=O)=O)cc3ccn(Cc4ccc(F)cc4)c23)c2cc[nH]c(=O)c12

InChI Key: InChIKey=WPUPAOCVMFTOLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539787 (CHEMBL4634252) Show SMILES Cn1cc(-c2cc(NS(C)(=O)=O)cc3ccn(Cc4ccc(F)cc4)c23)c2cc[nH]c(=O)c12 Show InChI InChI=1S/C24H21FN4O3S/c1-28-14-21(19-7-9-26-24(30)23(19)28)20-12-18(27-33(2,31)32)11-16-8-10-29(22(16)20)13-15-3-5-17(25)6-4-15/h3-12,14,27H,13H2,1-2H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair