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SMILES: Cc1cc(F)cc(C)c1Cn1ccc2cc(NS(C)(=O)=O)cc(-c3cn(C)c4c3cc[nH]c4=O)c12

InChI Key: InChIKey=NMQWRBJKKOKUNS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539789   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50539789
PNG
(CHEMBL4642629)
Show SMILES Cc1cc(F)cc(C)c1Cn1ccc2cc(NS(C)(=O)=O)cc(-c3cn(C)c4c3cc[nH]c4=O)c12
Show InChI InChI=1S/C26H25FN4O3S/c1-15-9-18(27)10-16(2)22(15)14-31-8-6-17-11-19(29-35(4,33)34)12-21(24(17)31)23-13-30(3)25-20(23)5-7-28-26(25)32/h5-13,29H,14H2,1-4H3,(H,28,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...

J Med Chem 63: 7186-7210 (2020)

More data for this
Ligand-Target Pair