BDBM50539790 CHEMBL4644325

SMILES: CCS(=O)(=O)Nc1cccc2n(Cc3ccc(F)cc3)c(nc12)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=RSHYCSPYNOUTHD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539790 (CHEMBL4644325) Show SMILES CCS(=O)(=O)Nc1cccc2n(Cc3ccc(F)cc3)c(nc12)-c1cn(C)c2c1cc[nH]c2=O Show InChI InChI=1S/C24H22FN5O3S/c1-3-34(32,33)28-19-5-4-6-20-21(19)27-23(30(20)13-15-7-9-16(25)10-8-15)18-14-29(2)22-17(18)11-12-26-24(22)31/h4-12,14,28H,3,13H2,1-2H3,(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair