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SMILES: CCS(=O)(=O)Nc1cc(cc2n(Cc3c(C)cccc3C)ccc12)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=KQXMGQLEUWRUDX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50539793
PNG
(CHEMBL4644443)
Show SMILES CCS(=O)(=O)Nc1cc(cc2n(Cc3c(C)cccc3C)ccc12)-c1cn(C)c2c1cc[nH]c2=O
Show InChI InChI=1S/C27H28N4O3S/c1-5-35(33,34)29-24-13-19(23-15-30(4)26-20(23)9-11-28-27(26)32)14-25-21(24)10-12-31(25)16-22-17(2)7-6-8-18(22)3/h6-15,29H,5,16H2,1-4H3,(H,28,32)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 158n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...

J Med Chem 63: 7186-7210 (2020)

More data for this
Ligand-Target Pair