BDBM50539794 CHEMBL4647786

SMILES: Cc1cccc(C)c1Cn1ccc2c(NS(C)(=O)=O)cc(cc12)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=NLYJWARCUOIKRE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539794 (CHEMBL4647786) Show SMILES Cc1cccc(C)c1Cn1ccc2c(NS(C)(=O)=O)cc(cc12)-c1cn(C)c2c1cc[nH]c2=O Show InChI InChI=1S/C26H26N4O3S/c1-16-6-5-7-17(2)21(16)15-30-11-9-20-23(28-34(4,32)33)12-18(13-24(20)30)22-14-29(3)25-19(22)8-10-27-26(25)31/h5-14,28H,15H2,1-4H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair