BDBM50539799 CHEMBL4638621

SMILES: CCS(=O)(=O)Nc1cc(cc2n(ccc12)C(c1ccccc1)c1ccccc1)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=GIKDMZZQRCLJSW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539799 (CHEMBL4638621) Show SMILES CCS(=O)(=O)Nc1cc(cc2n(ccc12)C(c1ccccc1)c1ccccc1)-c1cn(C)c2c1cc[nH]c2=O Show InChI InChI=1S/C31H28N4O3S/c1-3-39(37,38)33-27-18-23(26-20-34(2)30-24(26)14-16-32-31(30)36)19-28-25(27)15-17-35(28)29(21-10-6-4-7-11-21)22-12-8-5-9-13-22/h4-20,29,33H,3H2,1-2H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair