BDBM50539802 CHEMBL4647718

SMILES: CCC(c1ccccn1)(c1ccccn1)n1ccc2c(NS(=O)(=O)CC)cc(cc12)-c1cn(C)c2c1cc[nH]c2=O

InChI Key: InChIKey=DBSKJKYNRNKLDP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50539802 (CHEMBL4647718) Show SMILES CCC(c1ccccn1)(c1ccccn1)n1ccc2c(NS(=O)(=O)CC)cc(cc12)-c1cn(C)c2c1cc[nH]c2=O Show InChI InChI=1S/C31H30N6O3S/c1-4-31(27-10-6-8-14-32-27,28-11-7-9-15-33-28)37-17-13-23-25(35-41(39,40)5-2)18-21(19-26(23)37)24-20-36(3)29-22(24)12-16-34-30(29)38/h6-20,35H,4-5H2,1-3H3,(H,34,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of APC-labeled biotinylated-avidin from Euphorium-chelated recombinant human BRD4 bromodomain 1 expressed in Escherichia coli preincubat...				J Med Chem 63: 7186-7210 (2020)
					More data for this Ligand-Target Pair