BDBM50540561 CHEMBL4643748

SMILES: CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1

InChI Key: InChIKey=ZMCLBUHDJXZASC-NVQSTNCTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50540561 (CHEMBL4643748) Show SMILES CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O3/c1-4-5-20-29-27(32)28(2,3)34-26-15-11-22(12-16-26)19-21-33-25-17-13-24(14-18-25)31-30-23-9-7-6-8-10-23/h6-18H,4-5,19-21H2,1-3H3,(H,29,32)/b31-30+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020)
					More data for this Ligand-Target Pair