BDBM50540568 CHEMBL4634884

SMILES: CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1

InChI Key: InChIKey=WIGVJWVVWSUJEX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50540568 (CHEMBL4634884) Show SMILES CCCCNC(=O)C(C)(C)Oc1ccc(CCOc2ccc(NC(=O)Nc3ccccc3)cc2)cc1 Show InChI InChI=1S/C29H35N3O4/c1-4-5-20-30-27(33)29(2,3)36-26-15-11-22(12-16-26)19-21-35-25-17-13-24(14-18-25)32-28(34)31-23-9-7-6-8-10-23/h6-18H,4-5,19-21H2,1-3H3,(H,30,33)(H2,31,32,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
"G. d'Annunzio" University of Chieti-Pescara Curated by ChEMBL					Assay Description Antagonist activity at GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells assessed as inhibition of Wy14,643-induced receptor transactiva...				ACS Med Chem Lett 11: 624-632 (2020)
					More data for this Ligand-Target Pair