BDBM50540586 CHEMBL4633788

SMILES: O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1

InChI Key: InChIKey=SVXSDANQUOGVHF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 receptor (Cavia porcellus (Guinea pig))	BDBM50540586 (CHEMBL4633788) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O/c26-22(21-12-11-19-9-4-5-10-20(19)23-21)25-14-6-13-24(15-16-25)17-18-7-2-1-3-8-18/h1-5,7-12H,6,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540586 (CHEMBL4633788) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O/c26-22(21-12-11-19-9-4-5-10-20(19)23-21)25-14-6-13-24(15-16-25)17-18-7-2-1-3-8-18/h1-5,7-12H,6,13-17H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50540586 (CHEMBL4633788) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O/c26-22(21-12-11-19-9-4-5-10-20(19)23-21)25-14-6-13-24(15-16-25)17-18-7-2-1-3-8-18/h1-5,7-12H,6,13-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair