BDBM50540592 CHEMBL4643805

SMILES: Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1

InChI Key: InChIKey=NPKJCPIQHPJRBY-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-1 receptor (Cavia porcellus (Guinea pig))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...				ACS Med Chem Lett 11: 651-656 (2020)
					More data for this Ligand-Target Pair