BDBM50540594 CHEMBL4643145
SMILES: Cc1ccc(CN2CCCN(CC2)C(=O)c2ccncc2)c(C)c1
InChI Key: InChIKey=PJAULXQZQOWEPI-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human)) | BDBM50540594![]() (CHEMBL4643145) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s... | ACS Med Chem Lett 11: 651-656 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma-1 receptor (Cavia porcellus (Guinea pig)) | BDBM50540594![]() (CHEMBL4643145) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | 254 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method | ACS Med Chem Lett 11: 651-656 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma intracellular receptor 2 (Rattus norvegicus (Rat)) | BDBM50540594![]() (CHEMBL4643145) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method | ACS Med Chem Lett 11: 651-656 (2020) | |||||||||||
More data for this Ligand-Target Pair |