BDBM50540787 CHEMBL4648145

SMILES: CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1

InChI Key: InChIKey=HHVZZIQQDBBHDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540787 (CHEMBL4648145) Show SMILES CC(C)CCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C20H22FN5O/c1-14(2)6-7-18-13-26(25-24-18)19-10-8-16(9-11-19)22-20(27)23-17-5-3-4-15(21)12-17/h3-5,8-14H,6-7H2,1-2H3,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair