BDBM50540790 CHEMBL4640027

SMILES: CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1

InChI Key: InChIKey=ZSOXULDHZMCHLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540790 (CHEMBL4640027) Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 Show InChI InChI=1S/C19H20FN5O/c1-2-3-6-17-13-25(24-23-17)18-10-8-15(9-11-18)21-19(26)22-16-7-4-5-14(20)12-16/h4-5,7-13H,2-3,6H2,1H3,(H2,21,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair