BDBM50540792 CHEMBL4632918

SMILES: COc1cc(ccc1NC(=O)Nc1ccccc1C(F)(F)F)-n1cc(CCC(C)C)nn1

InChI Key: InChIKey=LZBPLDPFQQGZPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540792 (CHEMBL4632918) Show SMILES COc1cc(ccc1NC(=O)Nc1ccccc1C(F)(F)F)-n1cc(CCC(C)C)nn1 Show InChI InChI=1S/C22H24F3N5O2/c1-14(2)8-9-15-13-30(29-28-15)16-10-11-19(20(12-16)32-3)27-21(31)26-18-7-5-4-6-17(18)22(23,24)25/h4-7,10-14H,8-9H2,1-3H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair