BDBM50540795 CHEMBL4646961

SMILES: FCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1

InChI Key: InChIKey=DHOOSJWZEYJNCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540795 (CHEMBL4646961) Show SMILES FCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C17H13F4N5O/c18-9-12-10-26(25-24-12)13-7-5-11(6-8-13)22-16(27)23-15-4-2-1-3-14(15)17(19,20)21/h1-8,10H,9H2,(H2,22,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair