BDBM50540796 CHEMBL4638774

SMILES: Cc1ccccc1NC(=O)Nc1ccc(cc1)-n1cc(nn1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI Key: InChIKey=UOXKCYYVOWWOIS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540796 (CHEMBL4638774) Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-n1cc(nn1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F Show InChI InChI=1S/C20H14F9N5O/c1-11-4-2-3-5-14(11)31-16(35)30-12-6-8-13(9-7-12)34-10-15(32-33-34)17(21,22)18(23,24)19(25,26)20(27,28)29/h2-10H,1H3,(H2,30,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair