BDBM50540799 CHEMBL4635666

SMILES: CCCCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1

InChI Key: InChIKey=AXUZKXJUOIRMNL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50540799 (CHEMBL4635666) Show SMILES CCCCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C22H24F3N5O/c1-2-3-4-5-8-17-15-30(29-28-17)18-13-11-16(12-14-18)26-21(31)27-20-10-7-6-9-19(20)22(23,24)25/h6-7,9-15H,2-5,8H2,1H3,(H2,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...				ACS Med Chem Lett 11: 956-962 (2020)
					More data for this Ligand-Target Pair